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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRKAA2
All Species:
30.61
Human Site:
Y104
Identified Species:
56.11
UniProt:
P54646
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54646
NP_006243.2
552
62320
Y104
S
G
G
E
L
F
D
Y
I
C
K
H
G
R
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001086410
550
62775
Y106
S
G
G
E
L
F
D
Y
I
C
K
N
G
R
L
Dog
Lupus familis
XP_546691
722
81319
Y274
S
G
G
E
L
F
D
Y
I
C
K
H
G
R
V
Cat
Felis silvestris
Mouse
Mus musculus
Q8BRK8
552
61988
Y104
S
G
G
E
L
F
D
Y
I
C
K
H
G
R
V
Rat
Rattus norvegicus
Q09137
552
62239
Y104
S
G
G
E
L
F
D
Y
I
C
K
H
G
R
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506315
519
59478
S87
G
R
L
D
E
K
E
S
R
R
L
F
Q
Q
I
Chicken
Gallus gallus
Q9IA88
798
88848
H113
K
N
G
E
M
F
D
H
L
T
S
N
G
H
L
Frog
Xenopus laevis
NP_001088426
560
64038
Y115
S
G
G
E
L
F
D
Y
I
C
K
H
G
K
L
Zebra Danio
Brachydanio rerio
Q6NSM8
1187
130949
H146
S
G
G
E
I
F
D
H
L
V
A
H
G
R
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623371
515
58559
Y98
D
I
F
M
I
M
E
Y
V
S
G
G
E
L
F
Nematode Worm
Caenorhab. elegans
Q95ZQ4
626
70425
Y175
S
G
G
E
L
F
D
Y
I
V
K
H
G
R
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38997
535
61163
Y121
D
I
Y
L
V
M
E
Y
V
N
S
G
E
L
F
Baker's Yeast
Sacchar. cerevisiae
P06782
633
72027
I143
G
N
E
L
F
D
Y
I
V
Q
R
D
K
M
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
76.4
73.8
N.A.
97.6
98.1
N.A.
71.1
27.3
75.3
22.3
N.A.
N.A.
66.1
53.6
N.A.
Protein Similarity:
100
N.A.
86.7
75.2
N.A.
98.5
99
N.A.
81.1
42.6
85
32.6
N.A.
N.A.
77.7
65.6
N.A.
P-Site Identity:
100
N.A.
86.6
100
N.A.
100
100
N.A.
0
33.3
86.6
60
N.A.
N.A.
6.6
86.6
N.A.
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
26.6
66.6
100
86.6
N.A.
N.A.
26.6
93.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
44.9
33.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
62.3
50.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
47
0
0
0
0
0
% C
% Asp:
16
0
0
8
0
8
70
0
0
0
0
8
0
0
0
% D
% Glu:
0
0
8
70
8
0
24
0
0
0
0
0
16
0
0
% E
% Phe:
0
0
8
0
8
70
0
0
0
0
0
8
0
0
16
% F
% Gly:
16
62
70
0
0
0
0
0
0
0
8
16
70
0
0
% G
% His:
0
0
0
0
0
0
0
16
0
0
0
54
0
8
0
% H
% Ile:
0
16
0
0
16
0
0
8
54
0
0
0
0
0
8
% I
% Lys:
8
0
0
0
0
8
0
0
0
0
54
0
8
8
0
% K
% Leu:
0
0
8
16
54
0
0
0
16
0
8
0
0
16
31
% L
% Met:
0
0
0
8
8
16
0
0
0
0
0
0
0
8
8
% M
% Asn:
0
16
0
0
0
0
0
0
0
8
0
16
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
8
8
0
% Q
% Arg:
0
8
0
0
0
0
0
0
8
8
8
0
0
54
0
% R
% Ser:
62
0
0
0
0
0
0
8
0
8
16
0
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% T
% Val:
0
0
0
0
8
0
0
0
24
16
0
0
0
0
31
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
8
70
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _